郑敏实验室
郑敏
教授,博士生导师
研究方向:传染病学、慢性及重症肝病的发病机制和精准诊疗
郑敏

代表性论著

Selected Publications

1.Chen Y, Yao H, Zhang N, Wu J, Gao S, Guo J, Lu X, Cheng L, Luo R, Liang X, Wong CCL*, Zheng M*. Proteomic Analysis Identifies Prolonged Disturbances in Pathways Related to Cholesterol Metabolism and Myocardium Function in the COVID-19 Recovery Stage. J Proteome Res. 2021 Jul 2;20(7):3463-3474.

2. Wu H, Xu X, Zheng A, Wang W, Mei L, Chen Y, Sun S, Jiang L, Wu Y, Zhou Y, Zheng M*, Chen Q#. TIPE1 Inhibits Hepatic Steatosis, Inflammation, and Fibrosis by Suppressing Polyubiquitination of ASK1. Hepatology. 2021 Sep;74(3):1251-1270.

3. Yao H, Lu X, Chen Q, Xu K, Chen Y, Cheng M, Chen K, Cheng L, Weng T, Shi D, Liu F, Wu Z, Xie M, Wu H, Jin C, Zheng M*, Wu N#, Jiang C#, Li L#. Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo. Cell Discov. 2020 Oct 29;6(1):76.

4. Shi D, Weng T, Wu J, Dai C, Luo R, Chen K, Zhu M, Lu X, Cheng L, Chen Q, Liu F, Wu Z, Wu H, Jin C, Guo M, Chen Z, Wu N, Yao H#, Zheng M*. Dynamic Characteristic Analysis of Antibodies in Patients With COVID-19: A 13-Month Study. Front Immunol. 2021 Jul 20;12:708184.

5. Ruan D, Shi Y, Wen J, Zheng N#, Zheng M*. Spatially-Aware Context Neural Networks. IEEE Trans Image Process. 2021;30:6906-6916.

6. Ruan D, Shi Y, Jin L, Yang Q, Yu W, Ren H, Zheng W, Chen Y, Zheng N#, Zheng M*. An Ultrasound Image-Based Deep Multi-Scale Texture Network for Liver Fibrosis Grading in Patients with Chronic HBV Infection. Liver Int. 2021 Oct;41(10):2440-2454. 

7. Li S, Shao J, Lou G, Wu C, Liu Y#, Zheng M*. MiR-144-3p-mediated dysregulation of EIF4G2 contributes to the development of hepatocellular carcinoma through the ERK pathway. J Exp Clin Cancer Res. 2021 Feb 1;40(1):53.

8.  Xie M, Guo H, Lou G, Yao J, Liu Y, Sun Y#, Yang Z#, Zheng M*. Neddylation inhibitor MLN4924 has anti-HBV activity via modulating the ERK-HNF1α-C/EBPα-HNF4α axis. J Cell Mol Med. 2021 Jan;25(2):840-854.

9. Yetian Dong, Tong Dai, Yujun Wei, Long Zhang, Min Zheng*, Fangfang Zhou#. A systematic review of SARS-CoV-2 vaccine candidates. Signal Transduct Target Ther. 2020 Oct 13;5(1):237.

10. Shi Y, Zheng M*. Hepatitis B virus persistence and reactivation. BMJ. 2020 Sep 1;370:m2200.

11. Liu X, Zhang X, Peng Z, Li C, Wang Z, Wang C, Deng Z, Wu B, Cui Y, Wang Z, Cui CP#, Zheng M*, Zhang L#. Deubiquitylase OTUD6B Governs pVHL Stability in an Enzyme-Independent Manner and Suppresses Hepatocellular Carcinoma Metastasis. Adv Sci (Weinh). 2020 Mar 8;7(8):1902040.

12. Xiao Z, Cheng G, Jiao Y, Pan C, Li R, Jia D, Zhu J, Wu C#, Zheng M*, Jia J#. Holo-Seq: single-cell sequencing of holo-transcriptome. Genome Biol. 2018 Oct 17;19(1):163.

13. Liu Y#, Lou G, Li A, Zhang T, Qi J, Ye D, Zheng M*, Chen Z. AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages. EBioMedicine. 2018, 36:140-150.

14. Lou G, Chen L, Xia C, Wang W, Qi J, Li A, Zhao L, Chen Z, Zheng M*, Liu Y#. MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway. J ExpClin Cancer Res. 2020 Jan 2;39(1):4.

15. Li S, Yao J, Xie M, Liu Y, Zheng M*. Exosomal miRNAs in hepatocellular carcinoma development and clinical responses. J HematolOncol. 2018 Apr 11;11(1):54.



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