- CLOCK acetylates PRPS to promote de novo nucleotide synthesis and tumor growth
The biological clock is the timing controller of life activities, maintaining the orderly coordination of life activities at the organ tissue and cell levels, and presenting a clear circadian rhythm. The disturbance of the biological clock is closely rela...
CreateTime：2023-08-21 View：1223 - Daqian Xu's and Zhimin Lu's teams discover new ferroptosis regulatory pathway
Activation of receptor protein kinases is ubiquitous in various cancers, and the impact on ferroptosis is unknown.On May 8, 2023, Xu Daqian, Lu Zhimin of Zhejiang University published a paper entitled " Creatine kinase B suppresses ferroptosis by pho...
CreateTime：2023-05-16 View：1704 - Daqian Xu/Zhimin Lu Nature Cell Biology pubilshed: Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function
https://www.nature.com/articles/s41556-023-01133-9...
CreateTime：2023-05-09 View：1598 - Ben Wang's team ACS Nano published: Chemoimmunological Cascade Cancer Therapy Using Fluorine Assembly Nanomedicine
https://pubs.acs.org/doi/10.1021/acsnano.2c12600...
CreateTime：2023-04-07 View：1374 - Jinghai Chen's team Nature Communications published: A defect in mitochondrial protein translation influences mitonuclear communication in the heart
http://nature.com/articles/s41467-023-37291-5...
CreateTime：2023-04-03 View：1453 - Zhimin Lu's team Molecular Cell published: gatekeeping microglial activity by tuning glucose metabolism and mitochondrial functions
https://www.sciencedirect.com/science/article/pii/S1097276523001491...
CreateTime：2023-03-17 View：1311 - Daqian Xu and Zhimin Lu's team Nat Cell Biol published: Nucleus-exported CLOCK acetylates PRPS to promote de novo nucleotide synthesis and tumor growth
https://doi.org/10.1038/s41556-022-01061-0...
CreateTime：2023-03-15 View：1347 - Yi Sun's team J Clin Invest pubilshed: The UBE2C/CDH1/DEPTOR axis is an oncogene-tumor suppressor cascade in lung cancer cells
https://www.jci.org/articles/view/162434...
CreateTime：2023-03-01 View：1116
